Stability of early-stage amyloid-β(1–42) aggregation species
نویسندگان
چکیده
منابع مشابه
Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation
The aggregation of amyloid-β peptides into protein fibres is one of the main neuropathological features of Alzheimer's disease (AD). While imaging of amyloid-β aggregate morphology in vitro is extremely important for understanding AD pathology and in the development of aggregation inhibitors, unfortunately, potentially highly toxic, early aggregates are difficult to observe by current electron ...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
سال: 2013
ISSN: 1570-9639
DOI: 10.1016/j.bbapap.2012.08.017